Determination of a No-Observable Effect Level for Endotoxin Following a Single Intravitreal Administration to Dutch Belted Rabbits
Invest Ophthalmol Vis Sci. 2017 Mar 1;58(3):1545-1552. doi: 10.1167/iovs.16-21356.
ABSTRACT
PURPOSE: The purpose of this study was to characterize the inflammatory response and determine a no-observable effect level (NOEL) in rabbit eyes after endotoxin intravitreal (ITV) injection.