Development of choroidal neovascularization in rats with advanced intense cyclic light-induced retinal degeneration
Chris Murphy, DVM, Ph.D., DAVCO, founder and CEO of Ocular Services on Demand (OSOD, LLC) and EyeKor, LLC, is the recipient of the 2015 career achievement award in ocular toxicology from the Ocular Toxicology Specialty Section of the Society of Toxicology.
The ability of light to enact damage on the neurosensory retina and underlying structures has been well understood for hundreds of years. While the eye has adapted several mechanisms to protect itself from such damage, certain exposures to light can still result in temporal or permanent damage. Both clinical observations and laboratory studies have enabled us to understand the various ways by which the eye can protect itself from such damage. Light or electromagnetic radiation can result in damage through photothermal, photomechanical, and photochemical mechanisms.