Sinusoidal Stimulation - Cutting Edge Research

ERG frequency-response traces obtained by sinusoidal light stimulus

Vision scientists at OSOD are utilizing customized stimuli and analysis techniques to advance understanding of drug effects on the visual system in a non-clinical setting.

Integrating state-of-the-art vision science into the complex process of novel drug development requires specialized equipment and expertise.  When a sponsor’s needs are not met by the standard electroretinogram (ERG), vision scientists at OSOD work with clients to create custom protocols to achieve their project goals.

Using the Diagnosys™ system and customized frequency-domain analyses, OSOD implemented a protocol using mono-wavelength light sinusoidally modulated across a wide range of temporal frequencies to localize test article effects to specific retinal layers.  

OSOD uses cutting-edge instrumentation, combined with decades of preclinical and clinical experience, to advance the development of new therapies and diagnostic tools with the goal of improving the quality of life for patients.

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