Vijay K. Raghunathan, PhD

Dr. Raghunathan is a Bioengineer in the Department of Surgical and Radiological Sciences at the University of California, Davis. He is cross trained in biomaterials, biomechanics, and cell and molecular biology with research interests and expertise in drug delivery, force microscopy, toxicology, tissue engineering and medical device development for orthopedic, wound healing, and ocular applications. 

Recent Publications

2017

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Tissue and cellular biomechanics during corneal wound injury and repair.

Acta Biomater. 2017 May 27;:

Authors: Raghunathan VK, Thomasy SM, Strøm P, Yañez-Soto B, Garland SP, Sermeno J, Reilly CM, Murphy CJ

2016

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Species variation and spatial differences in mucin expression from corneal epithelial cells.

Exp Eye Res. 2016 Sep 8;152:43-48

Authors: Leonard BC, Yañez-Soto B, Raghunathan VK, Abbott NL, Murphy CJ

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Sensing Conductive Hydrogels for Rapid Detection of Cytokines in Blood.

Adv Healthc Mater. 2016 Jan 22;

Authors: Shin DS, Matharu Z, You J, Siltanen C, Vu T, Raghunathan VK, Stybayeva G, Hill AE, Revzin A

2015

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Effect of Stratification on Surface Properties of Corneal Epithelial Cells.

Invest Ophthalmol Vis Sci. 2015 Dec 1;56(13):8340-8

Authors: Yáñez-Soto B, Leonard BC, Raghunathan VK, Abbott NL, Murphy CJ

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Dexamethasone Stiffens Trabecular Meshwork, Trabecular Meshwork Cells, and Matrix.

Invest Ophthalmol Vis Sci. 2015 Jul 1;56(8):4447-59

Authors: Raghunathan VK, Morgan JT, Park SA, Weber D, Phinney BS, Murphy CJ, Russell P

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The intrinsic stiffness of human trabecular meshwork cells increases with senescence.

Oncotarget. 2015 Jun 20;6(17):15362-74

Authors: Morgan JT, Raghunathan VK, Chang YR, Murphy CJ, Russell P

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A Comparative Study of Vertebrate Corneal Structure: The Evolution of a Refractive Lens.

Invest Ophthalmol Vis Sci. 2015 Apr 1;56(4):2764-72

Authors: Winkler M, Shoa G, Tran ST, Xie Y, Thomasy S, Raghunathan VK, Murphy C, Brown DJ, Jester JV

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Wnt inhibition induces persistent increases in intrinsic stiffness of human trabecular meshwork cells.

Exp Eye Res. 2015 Jan 29;

Authors: Morgan JT, Raghunathan VK, Chang YR, Murphy CJ, Russell P

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Biomimetic stochastic topography and electric fields synergistically enhance directional migration of corneal epithelial cells in a MMP-3-dependent manner.

Acta Biomater. 2015 Jan 15;12:102-12

Authors: Gao J, Raghunathan VK, Reid B, Wei D, Diaz RC, Russell P, Murphy CJ, Zhao M

2014

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Assessment of platelet-derived growth factor using A splinted full thickness dermal wound model in bearded dragons (Pogona vitticeps).

J Zoo Wildl Med. 2014 Dec;45(4):866-74

Authors: Keller KA, Paul-Murphy J, Weber EP, Kass PH, Guzman SM, Park SA, Raghunathan VK, Gustavsen KA, Murphy CJ

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Automated AFM force curve analysis for determining elastic modulus of biomaterials and biological samples.

J Mech Behav Biomed Mater. 2014 Sep;37:209-18

Authors: Chang YR, Raghunathan VK, Garland SP, Morgan JT, Russell P, Murphy CJ

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Impact of Nanotopography, Heparin Hydrogel Microstructures, and Encapsulated Fibroblasts on Phenotype of Primary Hepatocytes.

ACS Appl Mater Interfaces. 2014 Sep 23;

Authors: You J, Raghunathan VK, Son KJ, Patel D, Haque A, Murphy CJ, Revzin A

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Epidermal growth factor-functionalized polymeric multilayer films: interplay between spatial location and bioavailability of EGF.

J Invest Dermatol. 2014 Jun;134(6):1757-60

Authors: Gorouhi F, Shah NM, Raghunathan VK, Mohabbati Y, Abbott NL, Isseroff RR, Murphy CJ

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A cell culture substrate with biologically relevant size-scale topography and compliance of the basement membrane.

Langmuir. 2014 Mar 4;30(8):2101-8

Authors: Garland SP, McKee CT, Chang YR, Raghunathan VK, Russell P, Murphy CJ

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Elastic modulus and collagen organization of the rabbit cornea: epithelium to endothelium.

Acta Biomater. 2014 Feb;10(2):785-91

Authors: Thomasy SM, Raghunathan VK, Winkler M, Reilly CM, Sadeli AR, Russell P, Jester JV, Murphy CJ

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Photopatternable and photoactive hydrogel for on-demand generation of hydrogen peroxide in cell culture.

Biomaterials. 2014 Feb;35(5):1762-70

Authors: Garland SP, Wang RY, Raghunathan VK, Lam KS, Murphy CJ, Russell P, Sun G, Pan T

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Robust and artifact-free mounting of tissue samples for atomic force microscopy.

Biotechniques. 2014 Jan;56(1):40-2

Authors: Morgan JT, Raghunathan VK, Thomasy SM, Murphy CJ, Russell P

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Human trabecular meshwork cells exhibit several characteristics of, but are distinct from, adipose-derived mesenchymal stem cells.

J Ocul Pharmacol Ther. 2014 Mar-Apr;30(2-3):254-66

Authors: Morgan JT, Wood JA, Walker NJ, Raghunathan VK, Borjesson DL, Murphy CJ, Russell P

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Full-thickness splinted skin wound healing models in db/db and heterozygous mice: implications for wound healing impairment.

Wound Repair Regen. 2014 May-Jun;22(3):368-80

Authors: Park SA, Teixeira LB, Raghunathan VK, Covert J, Dubielzig RR, Isseroff RR, Schurr M, Abbott NL, McAnulty J, Murphy CJ

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PDGF-BB does not accelerate healing in diabetic mice with splinted skin wounds.

PLoS One. 2014;9(8):e104447

Authors: Park SA, Raghunathan VK, Shah NM, Teixeira L, Motta MJ, Covert J, Dubielzig R, Schurr M, Isseroff RR, Abbott NL, McAnulty J, Murphy CJ

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Involvement of YAP, TAZ and HSP90 in contact guidance and intercellular junction formation in corneal epithelial cells.

PLoS One. 2014;9(10):e109811

Authors: Raghunathan VK, Dreier B, Morgan JT, Tuyen BC, Rose BW, Reilly CM, Russell P, Murphy CJ

2013

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Substratum compliance modulates corneal fibroblast to myofibroblast transformation.

Invest Ophthalmol Vis Sci. 2013;54(8):5901-7

Authors: Dreier B, Thomasy SM, Mendonsa R, Raghunathan VK, Russell P, Murphy CJ