Simon R. Cherry, PhD

Dr. Cherry is Professor in the Department of Biomedical Engineering and Director of the Center for Molecular and Genomic Imaging at the University of California, Davis.  Dr. Cherry’s research interests center around biomedical imaging and in particular the development and application of in vivo molecular imaging technology and systems, with specific expertise in positron emission tomography (PET) and optical imaging and their application in preclinical research. The technologies developed by his laboratory have been broadly applied in biomedical science to study disease processes and measure the effects of novel therapeutic interventions. Dr. Cherry is an elected fellow of five professional societies, including the Institute for Electronic and Electrical Engineers (IEEE) and the Biomedical Engineering Society (BMES). He is Editor-in-Chief of the journal Physics in Medicine and Biology. Dr. Cherry is the author of more than 200 peer-reviewed journal articles, review articles and book chapters in the field of biomedical imaging. 

To learn more about Dr. Cherry’s research, please click here: 

Recent Publications

2017

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Total-body imaging: Transforming the role of positron emission tomography.

Sci Transl Med. 2017 Mar 15;9(381):

Authors: Cherry SR, Badawi RD, Karp JS, Moses WW, Price P, Jones T

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Pair bond Formation Leads to a Sustained Increase in Global Cerebral Glucose Metabolism in Monogamous Male Titi Monkeys (Callicebus cupreus).

Neuroscience. 2017 Feb 24;:

Authors: Maninger N, Hinde K, Mendoza SP, Mason WA, Larke RH, Ragen BJ, Jarcho MR, Cherry SR, Rowland DJ, Ferrer E, Bales KL

Quantitative image reconstruction for total-body PET imaging using the 2-meter long EXPLORER scanner.

Phys Med Biol. 2017 Feb 27;62(6):2465-2485

Authors: Zhang X, Zhou J, Cherry SR, Badawi RD, Qi J

2016

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IPEM codes of practice and topical report series.

Phys Med Biol. 2016 Dec 7;61(23):E5-E6

Authors: Castellano EA, Eaton DJ, MacDougall ND, Cherry SR

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Improving Depth, Energy and Timing Estimation in PET Detectors with Deconvolution and Maximum Likelihood Pulse Shape Discrimination.

IEEE Trans Med Imaging. 2016 Nov;35(11):2436-2446

Authors: Berg E, Roncali E, Hutchcroft W, Qi J, Cherry SR

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Persistent neuroinflammation and cognitive impairment in a rat model of acute diisopropylfluorophosphate intoxication.

J Neuroinflammation. 2016 Oct 12;13(1):267

Authors: Flannery BM, Bruun DA, Rowland DJ, Banks CN, Austin AT, Kukis DL, Li Y, Ford BD, Tancredi DJ, Silverman JL, Cherry SR, Lein PJ

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Reaching 200-ps timing resolution in a time-of-flight and depth-of-interaction positron emission tomography detector using phosphor-coated crystals and high-density silicon photomultipliers.

J Med Imaging (Bellingham). 2016 Oct;3(4):043501

Authors: Kwon SI, Ferri A, Gola A, Berg E, Piemonte C, Cherry SR, Roncali E

Effects of pair bonding on dopamine D1 receptors in monogamous male titi monkeys (Callicebus cupreus).

Am J Primatol. 2016 Oct 18;:

Authors: Hostetler CM, Hinde K, Maninger N, Mendoza SP, Mason WA, Rowland DJ, Wang GB, Kukis D, Cherry SR, Bales KL

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Roberts Prize for the best paper published in 2015.

Phys Med Biol. 2016 Oct 07;61(21):E3-E4

Authors: Cherry SR, Simmons M

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Bismuth germanate coupled to near ultraviolet silicon photomultipliers for time-of-flight PET.

Phys Med Biol. 2016 Sep 2;61(18):L38-L47

Authors: Kwon SI, Gola A, Ferri A, Piemonte C, Cherry SR

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Developing a Nanoparticle-Delivered High-Efficacy Treatment for Infantile Hemangiomas Using a Mouse Hemangioendothelioma Model.

Plast Reconstr Surg. 2016 Aug;138(2):410-7

Authors: Orbay H, Li Y, Xiao W, Cherry SR, Lam K, Sahar DE

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A high resolution prototype small-animal PET scanner dedicated to mouse brain imaging.

J Nucl Med. 2016 Mar 24;

Authors: Yang Y, Bec J, Zhou J, Zhang M, Judenhofer MS, Bai X, Di K, Wu Y, Rodriguez M, Dokhale P, Shah K, Farrell R, Qi J, Cherry SR

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On the assessment of spatial resolution of PET systems with iterative image reconstruction.

Phys Med Biol. 2016 Mar 7;61(5):N193-202

Authors: Gong K, Cherry SR, Qi J

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Characterization of Large-Area SiPM Array for PET Applications.

IEEE Trans Nucl Sci. 2016 Feb;63(1):8-16

Authors: Du J, Yang Y, Bai X, Judenhofer MS, Berg E, Di K, Buckley S, Jackson C, Cherry SR

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A combined time-of-flight and depth-of-interaction detector for total-body positron emission tomography.

Med Phys. 2016 Feb;43(2):939

Authors: Berg E, Roncali E, Kapusta M, Du J, Cherry SR

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Activating Photodynamic Therapy in vitro with Cerenkov Radiation Generated from Yttrium-90.

J Environ Pathol Toxicol Oncol. 2016;35(2):185-92

Authors: Hartl BA, Hirschberg H, Marcu L, Cherry SR

Challenges to the Pair Bond: Neural and Hormonal Effects of Separation and Reunion in a Monogamous Primate.

Front Behav Neurosci. 2016;10:221

Authors: Hinde K, Muth C, Maninger N, Ragen BJ, Larke RH, Jarcho MR, Mendoza SP, Mason WA, Ferrer E, Cherry SR, Fisher-Phelps ML, Bales KL

2015

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Cherenkov luminescence measurements with digital silicon photomultipliers: a feasibility study.

EJNMMI Phys. 2015 Dec;2(1):32

Authors: Ciarrocchi E, Belcari N, Guerra AD, Cherry SR, Lehnert A, J Hunter WC, McDougald W, Miyaoka RS, Kinahan PE

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Roberts Prize for the best paper published in 2014.

Phys Med Biol. 2015 Sep 17;60(19):E1-E2

Authors: Cherry SR, Ruffle J

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Optimizing light transport in scintillation crystals for time-of-flight PET: an experimental and optical Monte Carlo simulation study.

Biomed Opt Express. 2015 Jun 1;6(6):2220-30

Authors: Berg E, Roncali E, Cherry SR

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Computed Cerenkov luminescence yields for radionuclides used in biology and medicine.

Phys Med Biol. 2015 May 14;60(11):4263-4280

Authors: Gill RK, Mitchell GS, Cherry SR

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Characterizing low fluence thresholds for in vitro photodynamic therapy.

Biomed Opt Express. 2015 Mar 1;6(3):770-9

Authors: Hartl BA, Hirschberg H, Marcu L, Cherry SR

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Evaluation of Matrix9 silicon photomultiplier array for small-animal PET.

Med Phys. 2015 Feb;42(2):585

Authors: Du J, Schmall JP, Yang Y, Di K, Roncali E, Mitchell GS, Buckley S, Jackson C, Cherry SR

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Validation of the SimSET simulation package for modeling the Siemens Biograph mCT PET scanner.

Phys Med Biol. 2015 Feb 7;60(3):N35-45

Authors: Poon JK, Dahlbom ML, Casey ME, Qi J, Cherry SR, Badawi RD

Un-collimated single-photon imaging system for high-sensitivity small animal and plant imaging.

Phys Med Biol. 2015 Jan 7;60(1):403-20

Authors: Walker KL, Judenhofer MS, Cherry SR, Mitchell GS

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Simultaneous PET/MRI Imaging During Mouse Cerebral Hypoxia-ischemia.

J Vis Exp. 2015;(103)

Authors: Ouyang Y, Judenhofer MS, Walton JH, Marik J, Williams SP, Cherry SR

2014

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Roberts Prize for the best paper published in 2013.

Phys Med Biol. 2014 Oct 21;59(20):5971-2

Authors: Cherry SR, Ruffle J

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Timing properties of phosphor-coated polished LSO crystals.

Phys Med Biol. 2014 Aug 7;59(15):N139-51

Authors: Schmall JP, Roncali E, Berg E, Viswanath V, Du J, Cherry SR

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Effects of reflector and crystal surface on the performance of a depth-encoding PET detector with dual-ended readout.

Med Phys. 2014 Jul;41(7):072503

Authors: Ren S, Yang Y, Cherry SR

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A Study of Position-Sensitive Solid-State Photomultiplier Signal Properties.

IEEE Trans Nucl Sci. 2014 Jun 12;61(3):1074-1083

Authors: Schmall JP, Du J, Judenhofer MS, Dokhale P, Christian J, McClish M, Shah KS, Cherry SR

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Evaluation of 2-[¹⁸F]fluoroacetate kinetics in rodent models of cerebral hypoxia-ischemia.

J Cereb Blood Flow Metab. 2014 May;34(5):836-44

Authors: Ouyang Y, Tinianow JN, Cherry SR, Marik J

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Ultra staging to unmask the prescribing of adjuvant therapy in cancer patients: the future opportunity to image micrometastases using total-body 18F-FDG PET scanning.

J Nucl Med. 2014 Apr;55(4):696-7

Authors: Price PM, Badawi RD, Cherry SR, Jones T

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Predicting the timing properties of phosphor-coated scintillators using Monte Carlo light transport simulation.

Phys Med Biol. 2014 Apr 21;59(8):2023-39

Authors: Roncali E, Schmall JP, Viswanath V, Berg E, Cherry SR

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Numerical simulation of x-ray luminescence optical tomography for small-animal imaging.

J Biomed Opt. 2014 Apr;19(4):046002

Authors: Li C, Martínez-Dávalos A, Cherry SR

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A Monte Carlo investigation of the spatial resolution performance of a small-animal PET scanner designed for mouse brain imaging studies.

Phys Med. 2014 Feb;30(1):76-85

Authors: Rodríguez-Villafuerte M, Yang Y, Cherry SR

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Performance and limitations of positron emission tomography (PET) scanners for imaging very low activity sources.

Phys Med. 2014 Feb;30(1):104-10

Authors: Freedenberg MI, Badawi RD, Tarantal AF, Cherry SR

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New shielding configurations for a simultaneous PET/MRI scanner at 7T.

J Magn Reson. 2014 Feb;239:50-6

Authors: Peng BJ, Wu Y, Cherry SR, Walton JH

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In vivo tracking of Th1 cells by PET reveals quantitative and temporal distribution and specific homing in lymphatic tissue.

J Nucl Med. 2014 Feb;55(2):301-7

Authors: Griessinger CM, Kehlbach R, Bukala D, Wiehr S, Bantleon R, Cay F, Schmid A, Braumüller H, Fehrenbacher B, Schaller M, Eichner M, Sutcliffe JL, Ehrlichmann W, Eibl O, Reischl G, Cherry SR, Röcken M, Pichler BJ, Kneilling M

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A smart and versatile theranostic nanomedicine platform based on nanoporphyrin.

Nat Commun. 2014;5:4712

Authors: Li Y, Lin TY, Luo Y, Liu Q, Xiao W, Guo W, Lac D, Zhang H, Feng C, Wachsmann-Hogiu S, Walton JH, Cherry SR, Rowland DJ, Kukis D, Pan C, Lam KS

2013

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X-ray luminescence optical tomography imaging: experimental studies.

Opt Lett. 2013 Jul 1;38(13):2339-41

Authors: Li C, Di K, Bec J, Cherry SR

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Simulation of light transport in scintillators based on 3D characterization of crystal surfaces.

Phys Med Biol. 2013 Apr 7;58(7):2185-98

Authors: Roncali E, Cherry SR

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Applications for preclinical PET/MRI.

Semin Nucl Med. 2013 Jan;43(1):19-29

Authors: Judenhofer MS, Cherry SR

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Radiolabeling human peripheral blood stem cells for positron emission tomography (PET) imaging in young rhesus monkeys.

PLoS One. 2013;8(10):e77148

Authors: Tarantal AF, Lee CC, Kukis DL, Cherry SR