Richard R. Dubielzig, DVM

Dr. Dubielzig is a founder, former managing member, and currently provides consulting on ocular pathology.

Dr. Dubielzig is a Board Certified Veterinary Pathologist, and Professor of Pathology, School of Veterinary Medicine, University of Wisconsin-Madison. He is primarily interested in comparative ocular pathology, but has written and lectured widely on diverse topics concerning veterinary ophthalmic pathology, laboratory animal ocular pathology and comparative ocular morphology.

Dr. Dubielzig has authored more than 200 publications, and is recognized for his ground-breaking observations of the spontaneous ocular diseases of animals. He runs an active mail-in ocular pathology service that processes more than 3000 specimens annually. He also provides consulting to industries on the development of ocular lesions.

To learn more about Dr. Dubielzig's research, please click here:

Recent Publications

2017

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Iridociliary cysts masquerading as neoplasia in cats: a morphologic review of 14 cases.

Vet Ophthalmol. 2017 Jul 06;:

Authors: Fragola JA, Dubielzig RR, Bentley E, Teixeira LBC

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Mandibular odontoameloblastoma in a rat and a horse.

J Vet Diagn Invest. 2017 May 01;:1040638717711996

Authors: Murphy B, Bell C, Koehne A, Dubielzig RR

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Do you see what I see? Optical morphology and visual capability of 'disco' clams (Ctenoides ales).

Biol Open. 2017 Apr 10;:

Authors: Dougherty LF, Dubielzig RR, Schobert CS, Teixeira LB, Li J

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Orbital rhabdomyosarcoma and traumatic neuroma following enucleation for a uveal schwannoma in a dog: a case report.

Clin Case Rep. 2017 Mar;5(3):300-307

Authors: McDonald JE, Knollinger AM, Teixeira LB, Dubielzig RR

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The consequences of avian ocular trauma: histopathological evidence and implications of acute and chronic disease.

Vet Ophthalmol. 2017 Jan 10;:

Authors: Moore BA, Teixeira LB, Sponsel WE, Dubielzig RR

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Diversity of Photoreceptor Arrangements in Nocturnal, Cathemeral and Diurnal Malagasy Lemurs.

J Comp Neurol. 2017 Jan 05;:

Authors: Peichl L, Kaiser A, Rakotondraparany F, Dubielzig RR, Goodman SM, Kappeler AP

2016

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Modeling the Chronic Loss of Optic Nerve Axons and the Effects on the Retinal Nerve Fiber Layer Structure in Primary Disorder of Myelin.

Invest Ophthalmol Vis Sci. 2016 Sep 1;57(11):4859-4868

Authors: Teixeira LB, Hoeve JN, Mayer JA, Dubielzig RR, Smith CM, Radcliff AB, Duncan ID

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Feline Epitheliotropic Mastocytic Conjunctivitis in 15 Cats.

Vet Pathol. 2016 Jul 1;

Authors: Beckwith-Cohen B, Dubielzig RR, Maggs DJ, Teixeira LB

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Late prostatic metastasis of an uveal melanoma in a miniature Schnauzer dog.

Clin Case Rep. 2016 Jul;4(7):647-52

Authors: Delgado E, Silva JX, Pissarra H, Peleteiro MC, Dubielzig RR

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Protozoal infections of the cornea and conjunctiva in dogs associated with chronic ocular surface disease and topical immunosuppression.

Vet Ophthalmol. 2016 May;19(3):206-13

Authors: Beckwith-Cohen B, Gasper DJ, Bentley E, Gittelman H, Ellis AE, Snowden KF, Shock BC, Yabsley MJ, Dubielzig RR

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Glaucoma with Descemet's membrane detachment in five horses.

Vet Ophthalmol. 2016 May 18;

Authors: Henriksen ML, La Croix N, Wilkie DA, Lassaline-Utter M, Brantman KR, Beamer GL, Teixeira LB, Dubielzig RR

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Suspected malignant transformation of B lymphocytes in the equine cornea from immune-mediated keratitis.

Vet Ophthalmol. 2016 Mar;19(2):172-9

Authors: Vallone LV, Neaderland MH, Ledbetter EC, Dubielzig RR

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Canine and feline retinal lymphoma: a retrospective review of 12 cases.

Vet Ophthalmol. 2016 Feb 12;

Authors: Malmberg JL, Garcia T, Dubielzig RR, Ehrhart EJ

2015

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Keratitis in six dogs after topical treatment with carbonic anhydrase inhibitors for glaucoma.

J Am Vet Med Assoc. 2015 Dec 15;247(12):1419-26

Authors: Beckwith-Cohen B, Bentley E, Gasper DJ, McLellan GJ, Dubielzig RR

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Unilateral ventral strabismus in an aquarium Silver Arowana (Osteoglossum bicirrhosum).

Vet Ophthalmol. 2015 Oct 6;

Authors: Chow DW, Westermeyer HD, Fernando N, Hoey S, Dubielzig RR

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The Significance of the Discordant Occurrence of Lens Tumors in Humans versus Other Species.

Ophthalmology. 2015 Jun 27;

Authors: Albert DM, Phelps PO, Surapaneni KR, Thuro BA, Potter HA, Ikeda A, Teixeira LB, Dubielzig RR

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Third eyelid gland neoplasms of dogs and cats: a retrospective histopathologic study of 145 cases.

Vet Ophthalmol. 2015 Apr 1;

Authors: Dees DD, Schobert CS, Dubielzig RR, Stein TJ

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Canine orbital rhabdomyosarcoma: a report of 18 cases.

Vet Ophthalmol. 2015 Apr 1;

Authors: Scott EM, Teixeira LB, Flanders DJ, Dubielzig RR, McLellan GJ

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Conjunctival habronemiasis in a square-lipped rhinoceros (Ceratotherium simum).

Vet Ophthalmol. 2015 Mar 28;

Authors: Horowitz IH, Dubielzig RR, Botero-Anug AM, Lucio-Forster A, Bowman DD, Rosenzweig AB, Frenkel S, Ofri R

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Short posterior ciliary artery anatomy in normal and acutely glaucomatous dogs.

Vet Ophthalmol. 2015 Feb 10;

Authors: Fick CM, Dubielzig RR

2014

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Outcome of iridociliary epithelial tumour biopsies in dogs: a retrospective study.

Vet Rec. 2014 Oct 15;

Authors: Beckwith-Cohen B, Bentley E, Dubielzig RR

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Squamous Papillomas of the Conjunctiva in Dogs: A Condition Not Associated With Papillomavirus Infection.

Vet Pathol. 2014 Oct 28;

Authors: Beckwith-Cohen B, Teixeira LB, Ramos-Vara JA, Dubielzig RR

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Clinical and histological characteristics of canine ocular gliovascular syndrome.

Vet Ophthalmol. 2014 Sep 1;

Authors: Treadwell A, Naranjo C, Blocker T, Zarfoss M, Dubielzig RR

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Presumed primary intraocular chondrosarcoma in cats.

J Vet Diagn Invest. 2014 Jul 23;

Authors: Beckwith-Cohen B, Teixeira LB, Dubielzig RR

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Full-thickness splinted skin wound healing models in db/db and heterozygous mice: Implications for wound healing impairment.

Wound Repair Regen. 2014 May;22(3):368-80

Authors: Park SA, Teixeira LB, Raghunathan VK, Covert J, Dubielzig RR, Isseroff RR, Schurr M, Abbott NL, McAnulty J, Murphy CJ

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Ultrastructural Abnormalities of the Trabecular Meshwork Extracellular Matrix in Cyp1b1-Deficient Mice.

Vet Pathol. 2014 May 30;

Authors: Teixeira LB, Zhao Y, Dubielzig RR, Sorenson CM, Sheibani N

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Periocular extracranial cutaneous meningiomas in two dogs.

J Vet Diagn Invest. 2014 May 6;

Authors: Teixeira LB, Pinkerton ME, Dubielzig RR

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Anchoring a cytoactive factor in a wound bed promotes healing.

J Tissue Eng Regen Med. 2014 Mar 27;

Authors: Chattopadhyay S, Guthrie KM, Teixeira L, Murphy CJ, Dubielzig RR, McAnulty JF, Raines RT

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Presumed solitary intraocular or conjunctival lymphoma in dogs and cats: 9 cases (1985-2013).

J Am Vet Med Assoc. 2014 Feb 15;244(4):460-70

Authors: Wiggans KT, Skorupski KA, Reilly CM, Frazier SA, Dubielzig RR, Maggs DJ

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Malignant Uveal Schwannoma With Peripheral Nerve Extension in a 12-Week-Old Color-Dilute Labrador Retriever.

Vet Pathol. 2014 Feb 10;

Authors: Duke FD, Teixeira LB, Galle LE, Green N, Dubielzig RR

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What is your diagnosis? Upper eyelid swelling in a dog.

Vet Clin Pathol. 2014 Jan 8;

Authors: Schappa JT, Peterson A, Dubielzig RR, Lim CC, Overmann JA

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Quantifying optic nerve axons in a cat glaucoma model by a semi-automated targeted counting method.

Mol Vis. 2014;20:376-85

Authors: Teixeira LB, Buhr KA, Bowie O, Duke FD, Nork TM, Dubielzig RR, McLellan GJ

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A Partial Gene Deletion of SLC45A2 Causes Oculocutaneous Albinism in Doberman Pinscher Dogs.

PLoS One. 2014;9(3):e92127

Authors: Winkler PA, Gornik KR, Ramsey DT, Dubielzig RR, Venta PJ, Petersen-Jones SM, Bartoe JT

2013

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Investigation of prognostic indicators for human uveal melanoma as biomarkers of canine uveal melanoma metastasis.

J Small Anim Pract. 2013 Nov;54(11):584-93

Authors: Malho P, Dunn K, Donaldson D, Dubielzig RR, Birand Z, Starkey M

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Subconjunctival hibernoma in a dog.

Vet Ophthalmol. 2013 Nov 18;

Authors: Stuckey JA, Rankin AJ, Romkes G, Slack J, Kiupel M, Dubielzig RR

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Histopathological study of the causes for failure of intrascleral prostheses in dogs and cats.

Vet Ophthalmol. 2013 Aug 1;

Authors: Naranjo C, Dubielzig RR

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Cyp1b1 Mediates Periostin Regulation of Trabecular Meshwork Development by Suppression of Oxidative Stress.

Mol Cell Biol. 2013 Aug 26;

Authors: Zhao Y, Wang S, Sorenson CM, Teixeira L, Dubielzig RR, Peters DM, Conway SJ, Jefcoate C, Sheibani N

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Comparison of ultrasonography and histologic examination for identification of ocular diseases of animals: 113 cases (2000-2010).

J Am Vet Med Assoc. 2013 Aug 1;243(3):376-88

Authors: Gallhoefer NS, Bentley E, Ruetten M, Grest P, Haessig M, Kircher PR, Dubielzig RR, Spiess BM, Pot SA

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Feline restrictive orbital myofibroblastic sarcoma in a cat - Cross sectional imaging (MRI & CT) appearance, treatment and outcome.

Vet Ophthalmol. 2013 Jul;16( 0):123-129

Authors: Thomasy SM, Cissell DD, Arzi B, Vilches-Moure JG, Lo WY, Wisner ER, Dubielzig RR, Maggs DJ

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Early histopathologic changes in the retina and optic nerve in canine primary angle-closure glaucoma.

Vet Ophthalmol. 2013 Jul;16 Suppl 1:79-86

Authors: Scott EM, Boursiquot N, Beltran WA, Dubielzig RR

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Clinical, Morphologic, and Immunohistochemical Features of Canine Orbital Hibernomas.

Vet Pathol. 2013 Jun 21;

Authors: Ravi M, Schobert CS, Kiupel M, Dubielzig RR

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Ocular comparative anatomy of the family Rodentia.

Vet Ophthalmol. 2013 Jun 5;

Authors: Rodriguez-Ramos Fernandez J, Dubielzig RR

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Primary primitive neuroectodermal tumors of the retina and ciliary body in dogs.

Vet Ophthalmol. 2013 May 15;

Authors: Regan DP, Dubielzig RR, Zeiss CJ, Charles B, Hoy SS, Ehrhart EJ

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Feline ocular tumors following ciliary body ablation with intravitreal gentamicin.

Vet Ophthalmol. 2013 May 22;

Authors: Duke FD, Strong TD, Bentley E, Dubielzig RR

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Integration of Silver Nanoparticle-impregnated Polyelectrolyte Multilayers Into Murine Splinted Cutaneous Wound Beds.

J Burn Care Res. 2013 Mar 18;

Authors: Guthrie KM, Agarwal A, Teixeira LB, Dubielzig RR, Abbott NL, Murphy CJ, Singh H, McAnulty JF, Schurr MJ

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Tapetal dysplasia in a Swedish Vallhund dog.

Vet Ophthalmol. 2013 Feb 13;

Authors: Scott EM, Teixeira LB, Dubielzig RR, Komáromy AM

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Major breed distribution of canine patients enucleated or eviscerated due to glaucoma following routine cataract surgery as well as common histopathologic findings within enucleated globes.

Vet Ophthalmol. 2013 Feb 13;

Authors: Scott EM, Esson DW, Fritz KJ, Dubielzig RR

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Restrictive orbital myofibroblastic sarcoma in a cat - Cross-sectional imaging (MRI & CT) appearance, treatment, and outcome.

Vet Ophthalmol. 2013 Jan 3;

Authors: Thomasy SM, Cissell DD, Arzi B, Vilches-Moure JG, Lo WY, Wisner ER, Dubielzig RR, Maggs DJ

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Metastatic uveal schwannoma of blue-eyed dogs.

Vet Ophthalmol. 2013 Jan 2;

Authors: Duke FD, Brudenall DK, Scott EM, Teixeira LB, Dubielzig RR

2012

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Canine ocular onchocercosis in the United States is associated with Onchocerca lupi.

Vet Parasitol. 2012 Dec 13;

Authors: Labelle AL, Maddox CW, Daniels JB, Lanka S, Eggett TE, Dubielzig RR, Labelle P

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Comparative ocular anatomy in a blind African cichlid fish, Lamprologus lethops.

Vet Ophthalmol. 2012 Nov 27;

Authors: Schobert CS, Stiassny ML, Schwab IR, Zeiss C, Schelly RC, Dubielzig RR

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An unusual case of ocular melanosis and limbal melanocytoma with benign intraorbital extension in a dog.

Vet Ophthalmol. 2012 Nov 7;

Authors: Dees DD, Maclaren NE, Teixeira L, Dubielzig RR

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Characterization of ocular gland morphology and tear composition of pinnipeds.

Vet Ophthalmol. 2012 Oct 15;

Authors: Davis RK, Doane MG, Knop E, Knop N, Dubielzig RR, Colitz CM, Argüeso P, Sullivan DA

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Metaherpetic corneal disease in a dog associated with partial limbal stem cell deficiency and neurotrophic keratitis.

Vet Ophthalmol. 2012 Sep 7;

Authors: Ledbetter EC, Marfurt CF, Dubielzig RR

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Canine ocular tumors following ciliary body ablation with intravitreal gentamicin.

Vet Ophthalmol. 2012 Jul 19;

Authors: Duke FD, Strong TD, Bentley E, Dubielzig RR

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Septic implantation syndrome in dogs and cats: a distinct pattern of endophthalmitis with lenticular abscess.

Vet Ophthalmol. 2012 Jul 19;

Authors: Bell CM, Pot SA, Dubielzig RR

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Histopathological and Immunohistochemical Features of Vitreoretinopathy in Shih Tzu Dogs.

J Comp Pathol. 2012 Jul 19;

Authors: Papaioannou NG, Dubielzig RR

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Systemic Distribution of Viral Antigen in Alpacas Persistently Infected With Bovine Pestivirus.

Vet Pathol. 2012 Jun 11;

Authors: Henningson JN, Steffen DJ, Topliff CL, Kurth KL, Dubielzig RR, Brodersen BW, Bedenice D, Eskridge KM, Callan RJ, Reggiardo C, Rupp GP, Kelling CL

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Bilateral Buphthalmia in a 4-Month-Old Texas Longhorn Steer.

Vet Pathol. 2012 Jun 11;

Authors: Jones ML, Beck AP, Dubielzig RR

Osteosarcoma of the Maxilla with Concurrent Osteoma in a Southern Sea Otter (Enhydra lutris nereis).

J Comp Pathol. 2012 Apr 18;

Authors: Rodriguez-Ramos Fernandez J, Thomas NJ, Dubielzig RR, Drees R

Functional and anatomic consequences of subretinal dosing in the cynomolgus macaque.

Arch Ophthalmol. 2012 Jan;130(1):65-75

Authors: Nork TM, Murphy CJ, Kim CB, Ver Hoeve JN, Rasmussen CA, Miller PE, Wabers HD, Neider MW, Dubielzig RR, McCulloh RJ, Christian BJ

2011

Ocular lesions following suspected lightning injury in a horse.

Vet Ophthalmol. 2011 Dec 28;

Authors: Evans PM, Armour MD, Dubielzig RR

Angiofibroma of the nasal cavity in 13 dogs.

Vet Comp Oncol. 2011 Dec;9(4):304-9

Authors: Burgess KE, Green EM, Wood RD, Dubielzig RR

Prevention of experimental choroidal neovascularization and resolution of active lesions by VEGF trap in nonhuman primates.

Arch Ophthalmol. 2011 Aug;129(8):1042-52

Authors: Nork TM, Dubielzig RR, Christian BJ, Miller PE, Miller JM, Cao J, Zimmer EP, Wiegand SJ

A slowly progressive retinopathy in the Shetland Sheepdog.

Vet Ophthalmol. 2011 Jul;14(4):227-38

Authors: Karlstam L, Hertil E, Zeiss C, Ropstad EO, Bjerkås E, Dubielzig RR, Ekesten B

Diagnostic features of feline restrictive orbital myofibroblastic sarcoma.

Vet Pathol. 2011 May;48(3):742-50

Authors: Bell CM, Schwarz T, Dubielzig RR

Canine conjunctival mast cell tumors: a retrospective study.

Vet Ophthalmol. 2011 May;14(3):153-60

Authors: Fife M, Blocker T, Fife T, Dubielzig RR, Dunn K

Superficial corneal squamous cell carcinoma occurring in dogs with chronic keratitis.

Vet Ophthalmol. 2011 May;14(3):161-8

Authors: Dreyfus J, Schobert CS, Dubielzig RR

Multiple congenital ocular anomalies in Icelandic horses.

BMC Vet Res. 2011;7:21

Authors: Andersson LS, Axelsson J, Dubielzig RR, Lindgren G, Ekesten B

2010

Anterior uveal spindle cell tumor in a cat.

Vet Ophthalmol. 2010 Nov;13(6):387-90

Authors: Evans PM, Lynch GL, Dubielzig RR

Kinetics of immune cell infiltration in vaccinia virus keratitis.

Invest Ophthalmol Vis Sci. 2010 Sep;51(9):4541-8

Authors: Altmann S, Toomey M, Nesbit B, McIntyre K, Covert J, Dubielzig RR, Leatherberry G, Adkins E, Murphy CJ, Brandt CR

A quantitative rabbit model of vaccinia keratitis.

Invest Ophthalmol Vis Sci. 2010 Sep;51(9):4531-40

Authors: Altmann S, Emanuel A, Toomey M, McIntyre K, Covert J, Dubielzig RR, Leatherberry G, Murphy CJ, Kodihalli S, Brandt CR

Anatomy of the California sea lion globe.

Vet Ophthalmol. 2010 Sep;13 Suppl:63-71

Authors: Miller SN, Colitz CM, Dubielzig RR

Orbital extraskeletal osteosarcoma following enucleation in a cat: a case report.

Vet Ophthalmol. 2010 May;13(3):179-83

Authors: Groskopf BS, Dubielzig RR, Beaumont SL

Canine mesenchymal hamartoma of the eyelid.

Vet Ophthalmol. 2010 Mar;13(2):94-8

Authors: Kafarnik C, Calvarese S, Dubielzig RR

Development of choroidal neovascularization in rats with advanced intense cyclic light-induced retinal degeneration.

Arch Ophthalmol. 2010 Feb;128(2):212-22

Authors: Albert DM, Neekhra A, Wang S, Darjatmoko SR, Sorenson CM, Dubielzig RR, Sheibani N

Canine pre-iridal fibrovascular membranes: morphologic and immunohistochemical investigations.

Vet Ophthalmol. 2010 Jan;13(1):4-13

Authors: Zarfoss MK, Breaux CB, Whiteley HE, Hamor RE, Flaws JA, Labelle P, Dubielzig RR

Feline conjunctival melanoma: histopathological characteristics and clinical outcomes.

Vet Ophthalmol. 2010 Jan;13(1):43-6

Authors: Schobert CS, Labelle P, Dubielzig RR

Computed tomography characteristics of canine tracheobronchial lymph node metastasis.

Vet Radiol Ultrasound. 2010 Jul-Aug;51(4):397-403

Authors: Ballegeer EA, Adams WM, Dubielzig RR, Paoloni MC, Klauer JM, Keuler NS

The PPCD1 mouse: characterization of a mouse model for posterior polymorphous corneal dystrophy and identification of a candidate gene.

PLoS One. 2010;5(8):e12213

Authors: Shen AL, O'Leary KA, Dubielzig RR, Drinkwater N, Murphy CJ, Kasper CB, Bradfield CA

Viral replication rate regulates clinical outcome and CD8 T cell responses during highly pathogenic H5N1 influenza virus infection in mice.

PLoS Pathog. 2010;6(10):e1001139

Authors: Hatta Y, Hershberger K, Shinya K, Proll SC, Dubielzig RR, Hatta M, Katze MG, Kawaoka Y, Suresh M

Proof of principle of ocular sparing in dogs with sinonasal tumors treated with intensity-modulated radiation therapy.

Vet Radiol Ultrasound. 2010 Sep-Oct;51(5):561-70

Authors: Lawrence JA, Forrest LJ, Turek MM, Miller PE, Mackie TR, Jaradat HA, Vail DM, Dubielzig RR, Chappell R, Mehta MP