Mark J. Mannis, MD

Dr. Mannis is Professor and Chair of the UC Davis Health System Eye Center.  He specializes in corneal transplantation and external diseases of the eye. His research has included development of experimental antimicrobial agents and growth factors that affect the corneal wound healing rate, skin diseases that affect the eye, and outcomes of corneal transplants and artificial corneas. Dr. Mannis has authored over 125 publications and five books on topics relating to corneal surgery and disease.

To learn more about Dr. Mannis' research, please click here:

Recent Publications


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Evaluation of a Portable Artificial Vision Device Among Patients With Low Vision.

JAMA Ophthalmol. 2016 May 5;

Authors: Moisseiev E, Mannis MJ

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Reply to Letter to the Editor: Ultrathin Grafts for DSAEK With a Single Microkeratome Pass.

Cornea. 2016 Feb 3;

Authors: Choulakian MY, Li JY, Ramos S, Mannis MJ


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Ocular Adverse Events Associated with Antibody-Drug Conjugates in Human Clinical Trials.

J Ocul Pharmacol Ther. 2015 Nov 5;

Authors: Eaton JS, Miller PE, Mannis MJ, Murphy CJ

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Single-Pass Microkeratome System for Eye Bank DSAEK Tissue Preparation: Is Stromal Bed Thickness Predictable and Reproducible?

Cornea. 2015 Nov 6;

Authors: Choulakian MY, Li JY, Ramos S, Mannis MJ

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Use of Scleral Lenses and Miniscleral Lenses After Penetrating Keratoplasty.

Eye Contact Lens. 2015 Jul 24;

Authors: Barnett M, Lien V, Li JY, Durbin-Johnson B, Mannis MJ

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In vivo volumetric depth-resolved vasculature imaging of human limbus and sclera with 1μm swept source phase-variance optical coherence angiography.

J Opt. 2015 Jun;17(6)

Authors: Poddar R, Zawadzki RJ, Cortés DE, Mannis MJ, Werner JS

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In vivo ocular imaging of the cornea of the normal female laboratory beagle using confocal microscopy.

Vet Ophthalmol. 2015 Mar 6;

Authors: Strom AR, Cortés DE, Thomasy SM, Kass PH, Mannis MJ, Murphy CJ

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In vivo evaluation of the cornea and conjunctiva of the normal laboratory beagle using time- and Fourier-domain optical coherence tomography and ultrasound pachymetry.

Vet Ophthalmol. 2015 Feb 10;

Authors: Strom AR, Cortés DE, Rasmussen CA, Thomasy SM, McIntyre K, Lee SF, Kass PH, Mannis MJ, Murphy CJ


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Factors Associated With Corneal Graft Survival in the Cornea Donor Study.

JAMA Ophthalmol. 2014 Oct 16;

Authors: Writing Committee for the Cornea Donor Study Research Group, Sugar A, Gal RL, Kollman C, Raghinaru D, Dontchev M, Croasdale CR, Feder RS, Holland EJ, Lass JH, Macy JI, Mannis MJ, Smith PW, Soukiasian SH, Beck RW

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Corneal graft rejection 10 years after penetrating keratoplasty in the cornea donor study.

Cornea. 2014 Oct;33(10):1003-

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Professor dr med oskar fehr: the fate of an outstanding german-jewish ophthalmologist: an early contributor to cornea and external disease.

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Interfacial Phenomena and the Ocular Surface.

Ocul Surf. 2014 Jul;12(3):178-201

Authors: Yañez-Soto B, Mannis MJ, Schwab IR, Li JY, Leonard BC, Abbott NL, Murphy CJ

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Simultaneous Surgery for Corneal Edema and Aphakia: DSEK and Placement of a Retropupillary Iris Claw Lens.

Cornea. 2014 Feb;33(2):19


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The effect of donor age on penetrating keratoplasty for endothelial disease: graft survival after 10 years in the cornea donor study.

Ophthalmology. 2013 Dec;120(12):2419-27

Authors: Writing Committee for the Cornea Donor Study Research Group, Mannis MJ, Holland EJ, Gal RL, Dontchev M, Kollman C, Raghinaru D, Dunn SP, Schultze RL, Verdier DD, Lass JH, Raber IM, Sugar J, Gorovoy MS, Sugar A, Stulting RD, Montoya MM, Penta JG, Benetz BA, Beck RW

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Donor age and factors related to endothelial cell loss 10 years after penetrating keratoplasty: specular microscopy ancillary study.

Ophthalmology. 2013 Dec;120(12):2428-35

Authors: Writing Committee for the Cornea Donor Study Research Group, Lass JH, Benetz BA, Gal RL, Kollman C, Raghinaru D, Dontchev M, Mannis MJ, Holland EJ, Chow C, McCoy K, Price FW, Sugar A, Verdier DD, Beck RW

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Ocular rosacea: Common and commonly missed.

J Am Acad Dermatol. 2013 Dec;69(6 Suppl 1):S36-41

Authors: Vieira AC, Mannis MJ

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Evaluation of Microbial Flora in Eyes With a Boston Type 1 Keratoprosthesis.

Cornea. 2013 Oct 17;

Authors: Lee SH, Mannis MJ, Shapiro B, Li JY, Polage C, Smith W

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Lessons in corneal structure and mechanics to guide the corneal surgeon.

Ophthalmology. 2013 Sep;120(9):1715-7

Authors: Jester JV, Murphy CJ, Winkler M, Bergmanson JP, Brown D, Steinert RF, Mannis MJ

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Three-dimensional anterior segment imaging in patients with type 1 Boston Keratoprosthesis with switchable full depth range swept source optical coherence tomography.

J Biomed Opt. 2013 Aug 1;18(8):86002

Authors: Raju P, Cortés DE, Werner JS, Mannis MJ, Zawadzki RJ

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Epithelial Downgrowth After Penetrating Keratoplasty: Imaging by High-Resolution Optical Coherence Tomography and In Vivo Confocal Microscopy.

Cornea. 2013 Aug 7;

Authors: Chen MC, Cortés DE, Harocopos G, Mannis MJ

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Eye Banking and Corneal Transplantation Communicable Adverse Incidents: Current Status and Project NOTIFY.

Cornea. 2013 Aug;32(8):1155-1166

Authors: Dubord PJ, Evans GD, Macsai MS, Mannis MJ, Glasser DB, Strong DM, Noël L, Fehily D

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High-Resolution Spectral Domain Anterior Segment Optical Coherence Tomography in Type 1 Boston Keratoprosthesis.

Cornea. 2013 Apr 12;

Authors: Shapiro BL, Cortés DE, Chin EK, Li JY, Werner JS, Redenbo E, Mannis MJ

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Standard Terminology and Labeling of Ocular Tissue for Transplantation.

Cornea. 2013 Mar 27;

Authors: Armitage WJ, Ashford P, Crow B, Dahl P, Dematteo J, Distler P, Gopinathan U, Madden PW, Mannis MJ, Moffatt SL, Ponzin D, Tan D

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Characterization of novel O-glycans isolated from tear and saliva of ocular rosacea patients.

J Proteome Res. 2013 Mar 1;12(3):1090-100

Authors: Ozcan S, An HJ, Vieira AC, Park GW, Kim JH, Mannis MJ, Lebrilla CB

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Endothelial Morphometric Measures to Predict Endothelial Graft Failure After Penetrating Keratoplasty.

JAMA Ophthalmol. 2013 Mar 14;:1-8

Authors: Benetz BA, Lass JH, Gal RL, Sugar A, Menegay H, Dontchev M, Kollman C, Beck RW, Mannis MJ, Holland EJ, Gorovoy M, Hannush SB, Bokosky JE, Caudill JW, for the Cornea Donor Study Investigator Group

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Anterior Segment OCT and Confocal Microscopy Findings in Atypical Corneal Intraepithelial Neoplasia.

Cornea. 2013 Mar 27;

Authors: Chin EK, Cortés DE, Lam A, Mannis MJ

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Corneal Thickness as a Predictor of Corneal Transplant Outcome.

Cornea. 2013 Jan 22;

Authors: Verdier DD, Sugar A, Baratz K, Beck R, Dontchev M, Dunn S, Gal RL, Holland EJ, Kollman C, Lass JH, Mannis MJ, Penta J, for the Cornea Donor Study Investigator Group

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Pediatric penetrating keratoplasty.

Int Ophthalmol Clin. 2013;53(2):59-70

Authors: O'Hara MA, Mannis MJ


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Impact of the cornea donor study on acceptance of corneas from older donors.

Cornea. 2012 Dec;31(12):1441-5

Authors: Sugar A, Montoya MM, Beck R, Cowden JW, Dontchev M, Gal RL, Kollman C, Malling J, Mannis MJ, Tennant B, Cornea Donor Study Investigator Group

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Intereye Asymmetry Detected by Scheimpflug Imaging in Subjects With Normal Corneas and Keratoconus.

Cornea. 2012 Dec 19;

Authors: Henriquez MA, Izquierdo L, Mannis MJ

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Effect of donor and recipient factors on corneal graft rejection.

Cornea. 2012 Oct;31(10):1141-7

Authors: Stulting RD, Sugar A, Beck R, Belin M, Dontchev M, Feder RS, Gal RL, Holland EJ, Kollman C, Mannis MJ, Price F, Stark W, Verdier DD, Cornea Donor Study Investigator Group

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Ocular rosacea--a review.

Arq Bras Oftalmol. 2012 Oct;75(5):363-9

Authors: Vieira AC, Höfling-Lima AL, Mannis MJ

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Practice patterns and opinions in the management of recurrent or chronic herpes zoster ophthalmicus.

Cornea. 2012 Jul;31(7):786-90

Authors: Sy A, McLeod SD, Cohen EJ, Margolis TP, Mannis MJ, Lietman TM, Acharya NR

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Glycomic analysis of tear and saliva in ocular rosacea patients: the search for a biomarker.

Ocul Surf. 2012 Jul;10(3):184-92

Authors: Vieira AC, An HJ, Ozcan S, Kim JH, Lebrilla CB, Mannis MJ

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Jupiter Scleral Lenses: the UC Davis Eye Center experience.

Eye Contact Lens. 2012 May;38(3):179-82

Authors: Pecego M, Barnett M, Mannis MJ, Durbin-Johnson B


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Contact lenses in the management of keratoconus.

Cornea. 2011 Dec;30(12):1510-6

Authors: Barnett M, Mannis MJ