Dennis, J. Hartigan-O'Connor, MD, PhD

Dr. Hartigan-O'Connor is an Assistant Professor of Medicine at the University of California, Davis.  His research is focused on mechanisms of tolerance and immune privilege, both in the adult eye and in the developing fetus.  His most recent work focuses on resilience of retinal immune privilege to inflammatory insults and neovascularization, as well as the potential of immunosuppressive drugs to maintain privilege despite these challenges.  His work has been published in leading journals including Science Translational Medicine and the Journal of Experimental Medicine.

To learn more about Dr. Hartigan-O'Connor's research, please click here:

Recent Publications


Related Articles

Exposure to SIV in utero results in reduced viral loads and altered responsiveness to postnatal challenge.

Sci Transl Med. 2015 Aug 12;7(300):300ra125

Authors: Baker CA, Swainson L, Lin DL, Wong S, Hartigan-O'Connor DJ, Lifson JD, Tarantal AF, McCune JM

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Persistent effects of early infant diet and associated microbiota on the juvenile immune system.

Gut Microbes. 2015 Jul 4;6(4):284-9

Authors: Narayan NR, Méndez-Lagares G, Ardeshir A, Lu D, Van Rompay KK, Hartigan-O'Connor DJ


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Breast-fed and bottle-fed infant rhesus macaques develop distinct gut microbiotas and immune systems.

Sci Transl Med. 2014 Sep 3;6(252):252ra120

Authors: Ardeshir A, Narayan NR, Méndez-Lagares G, Lu D, Rauch M, Huang Y, Van Rompay KK, Lynch SV, Hartigan-O'Connor DJ

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Monocyte activation by interferon α is associated with failure to achieve a sustained virologic response after treatment for hepatitis C virus infection.

J Infect Dis. 2014 May 15;209(10):1602-12

Authors: Hartigan-O'Connor DJ, Lin D, Ryan JC, Shvachko VA, Cozen ML, Segal MR, Terrault NA, Lanier LL, Manos MM, McCune JM


Related Articles

IL-7 production in murine lymphatic endothelial cells and induction in the setting of peripheral lymphopenia.

Int Immunol. 2013 Aug;25(8):471-83

Authors: Miller CN, Hartigan-O'Connor DJ, Lee MS, Laidlaw G, Cornelissen IP, Matloubian M, Coughlin SR, McDonald DM, McCune JM


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SIV replication in the infected rhesus macaque is limited by the size


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Th17 cells and regulatory T cells in elite control over HIV and SIV.

Curr Opin HIV AIDS. 2011 May;6(3):221-7

Authors: Hartigan-O'Connor DJ, Hirao LA, McCune JM, Dandekar S

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Development of cytomegalovirus (CMV) immune recovery uveitis is associated with Th17 cell depletion and poor systemic CMV-specific T cell responses.

Clin Infect Dis. 2011 Feb 1;52(3):409-17

Authors: Hartigan-O'Connor DJ, Jacobson MA, Tan QX, Sinclair E, Studies of Ocular Complications of AIDS Research Group

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The human fetal immune response to hepatitis C virus exposure in utero.

J Infect Dis. 2011 Jan 15;203(2):196-206

Authors: Babik JM, Cohan D, Monto A, Hartigan-O'Connor DJ, McCune JM