B'Ann Gabelt, MS

Ms. Gabelt is a Distinguished Scientist in the Department of Ophthalmology and Visual Sciences at the University of Wisconsin School of Medicine and Public Health.  She has 29 years of experience conducting ocular physiology studies related to glaucoma pharmacotherapy and anterior segment gene therapy in nonhuman primates.  These include intraocular pressure, aqueous humor formation, outflow facility and uveoscleral outflow.  She has also developed anterior segment organ-culture systems for pig, monkey, and cow which can be used to measure effects on trabecular outflow.

Recent Publications

2016

Related Articles

Effects of Latanoprost and Bimatoprost on the Expression of Molecules Relevant to Ocular Inflow and Outflow Pathways.

PLoS One. 2016;11(3):e0151644

Authors: Li X, He F, Gabelt BT, Wang Y, Cai S, Cao J, Fan N, Kaufman PL, Liu X

2015

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Rat, Mouse, and Primate Models of Chronic Glaucoma Show Sustained Elevation of Extracellular ATP and Altered Purinergic Signaling in the Posterior Eye.

Invest Ophthalmol Vis Sci. 2015 May 1;56(5):3075-3083

Authors: Lu W, Hu H, Sévigny J, Gabelt BT, Kaufman PL, Johnson EC, Morrison JC, Zode GS, Sheffield VC, Zhang X, Laties AM, Mitchell CH

Related Articles

Viral Vector Effects on Exoenzyme C3 Transferase Mediated Actin Disruption and on Outflow Facility.

Invest Ophthalmol Vis Sci. 2015 Mar 17;

Authors: Slauson SR, Peters DM, Schwinn MK, Kaufman PL, Gabelt BT, Brandt CR

2014

Related Articles

Identification of adult stem cells in Schwalbe's line region of the primate eye.

Invest Ophthalmol Vis Sci. 2014 Oct 16;

Authors: Braunger BM, Ademoglu B, Koschade SE, Fuchshofer R, Gabelt BT, Kiland JA, Hennes-Beean EA, Brunner KG, Kaufman PL, Tamm ER

Related Articles

Prospects for Lentiviral Vector Mediated Prostaglandin F Synthase Gene Delivery in Monkey Eyes In vivo.

Curr Eye Res. 2014 Feb 21;

Authors: Lee ES, Rasmussen CA, Filla MS, Slauson SR, Kolb AW, Peters DM, Kaufman PL, Gabelt BT, Brandt CR

2013

Related Articles

Effect of Nitric Oxide on Anterior Segment Physiology in Monkeys.

Invest Ophthalmol Vis Sci. 2013 Jun 25;

Authors: Heyne GW, Kiland JA, Kaufman PL, Gabelt BT

2012

1α,25-Dihydroxyvitamin D(3) and its analog, 2-methylene-19-nor-(20S)-1α,25-dihydroxyvitamin D(3) (2MD), suppress intraocular pressure in non-human primates.

Arch Biochem Biophys. 2012 Feb 1;518(1):53-60

Authors: Kutuzova GD, Gabelt BT, Kiland JA, Hennes-Beann EA, Kaufman PL, Deluca HF

Structure/Function studies and the effects of memantine in monkeys with experimental glaucoma.

Invest Ophthalmol Vis Sci. 2012;53(4):2368-76

Authors: Gabelt BT, Rasmussen CA, Tektas OY, Kim CB, Peterson JC, Nork TM, Hoeve JN, Lütjen-Drecoll E, Kaufman PL

2011

Effect of nitric oxide compounds on monkey ciliary muscle in vitro.

Exp Eye Res. 2011 Sep;93(3):321-7

Authors: Gabelt BT, Kaufman PL, Rasmussen CA

Relationship of aqueous outflow resistance to age and total volume perfused in rhesus and cynomolgus monkeys.

Invest Ophthalmol Vis Sci. 2011 Aug;52(9):6820-4

Authors: Kiland JA, Gabelt BT, Kaufman PL

2010

Sodium orthovanadate effect on outflow facility and intraocular pressure in live monkeys.

Exp Eye Res. 2010 Oct;91(4):486-90

Authors: Tan JC, Kiland JA, Gonzalez JM, Gabelt BT, Peters DM, Kaufman PL

Heparin II domain of fibronectin mediates contractility through an alpha4beta1 co-signaling pathway.

Exp Cell Res. 2010 May 15;316(9):1500-12

Authors: Schwinn MK, Gonzalez JM, Gabelt BT, Sheibani N, Kaufman PL, Peters DM

COCH transgene expression in cultured human trabecular meshwork cells and its effect on outflow facility in monkey organ cultured anterior segments.

Invest Ophthalmol Vis Sci. 2010 Apr;51(4):2060-6

Authors: Lee ES, Gabelt BT, Faralli JA, Peters DM, Brandt CR, Kaufman PL, Bhattacharya SK