Michael W. Neider, BA

Mr. Neider is Associate Director-Photographic Services, Fundus Photograph Reading Center, Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison. The reading center has extensive experience interfacing with industry in the interpretation of clinical trials as well as participating in pre-clinical studies.

Recent Publications

2013

Related Articles

The chinese american eye study: design and methods.

Ophthalmic Epidemiol. 2013 Dec;20(6):335-47

Authors: Varma R, Hsu C, Wang D, Torres M, Azen SP, Chinese American Eye Study Group

Related Articles

The chinese american eye study: design and methods.

Ophthalmic Epidemiol. 2013 Dec;20(6):335-47

Authors: Varma R, Hsu C, Wang D, Torres M, Azen SP, Chinese American Eye Study Group

Abstract
PURPOSE: To summarize the study design, operational strategies and procedures of the Chinese American Eye Study (CHES), a population-based assessment of the prevalence of visual impairment, ocular disease, and visual functioning in Chinese Americans.
METHODS: This population-based, cross-sectional study included 4570 Chinese participants aged 50 years and older, residing in the city of Monterey Park, California. Each eligible participant completed a detailed interview and eye examination. The interview included an assessment of demographic, behavioral and ocular risk factors and health-related and vision-related quality of life. The eye examination included measurements of visual acuity, intraocular pressure, visual fields, fundus and optic disc photography, a detailed anterior and posterior segment examination, and measurements of blood pressure, glycosylated hemoglobin levels, and blood glucose levels.
RESULTS: The objectives of the CHES are to obtain prevalence estimates of visual impairment, refractive error, diabetic retinopathy, open-angle and angle-closure glaucoma, lens opacities, and age-related macular degeneration in Chinese Americans. In addition, outcomes include effect estimates for risk factors associated with eye diseases. Lastly, CHES will investigate the genetic determinants of myopia and glaucoma.
CONCLUSION: The CHES will provide information about the prevalence and risk factors of ocular diseases in one of the fastest growing minority groups in the United States.

PMID: 24044409 [PubMed - indexed for MEDLINE]

Related Articles

The chinese american eye study: design and methods.

Ophthalmic Epidemiol. 2013 Dec;20(6):335-47

Authors: Varma R, Hsu C, Wang D, Torres M, Azen SP, Chinese American Eye Study Group

2011

Related Articles

Population and high-risk group screening for glaucoma: the Los Angeles Latino Eye Study.

Invest Ophthalmol Vis Sci. 2011 Aug 05;52(9):6257-64

Authors: Francis BA, Varma R, Vigen C, Lai MY, Winarko J, Nguyen B, Azen S, Los Angeles Latino Eye Study Group

Related Articles

Population and high-risk group screening for glaucoma: the Los Angeles Latino Eye Study.

Invest Ophthalmol Vis Sci. 2011 Aug 05;52(9):6257-64

Authors: Francis BA, Varma R, Vigen C, Lai MY, Winarko J, Nguyen B, Azen S, Los Angeles Latino Eye Study Group

Abstract
PURPOSE: To evaluate the ability of various screening tests, both individually and in combination, to detect glaucoma in the general Latino population and high-risk subgroups.
METHODS: The Los Angeles Latino Eye Study is a population-based study of eye disease in Latinos 40 years of age and older. Participants (n = 6082) underwent Humphrey visual field testing (HVF), frequency doubling technology (FDT) perimetry, measurement of intraocular pressure (IOP) and central corneal thickness (CCT), and independent assessment of optic nerve vertical cup disc (C/D) ratio. Screening parameters were evaluated for three definitions of glaucoma based on optic disc, visual field, and a combination of both. Analyses were also conducted for high-risk subgroups (family history of glaucoma, diabetes mellitus, and age ≥65 years). Sensitivity, specificity, and receiver operating characteristic curves were calculated for those continuous parameters independently associated with glaucoma. Classification and regression tree (CART) analysis was used to develop a multivariate algorithm for glaucoma screening.
RESULTS: Preset cutoffs for screening parameters yielded a generally poor balance of sensitivity and specificity (sensitivity/specificity for IOP ≥21 mm Hg and C/D ≥0.8 was 0.24/0.97 and 0.60/0.98, respectively). Assessment of high-risk subgroups did not improve the sensitivity/specificity of individual screening parameters. A CART analysis using multiple screening parameters-C/D, HVF, and IOP-substantially improved the balance of sensitivity and specificity (sensitivity/specificity 0.92/0.92).
CONCLUSIONS: No single screening parameter is useful for glaucoma screening. However, a combination of vertical C/D ratio, HVF, and IOP provides the best balance of sensitivity/specificity and is likely to provide the highest yield in glaucoma screening programs.

PMID: 21245400 [PubMed - indexed for MEDLINE]

Related Articles

Population and high-risk group screening for glaucoma: the Los Angeles Latino Eye Study.

Invest Ophthalmol Vis Sci. 2011 Aug 05;52(9):6257-64

Authors: Francis BA, Varma R, Vigen C, Lai MY, Winarko J, Nguyen B, Azen S, Los Angeles Latino Eye Study Group