Animal Models

OSOD has considerable experience over many years with the following in vivo ocular disease models at Covance, Inc.:

  • Laser induced choroidal neovascularization (CNV) 
  • Corneal wound healing
  • Corneal implantable devices
  • Laser induced glaucoma  
  • Meibomian gland dysfunction

OSOD university-based experts also have experience with a broad range of animal models within a variety of species (rodent, rabbit, dog, cat). 

 Rodent models:

  • Choroidal neovascularization (CNV) 
  • Retinopathy of prematurity (ROP) 
  • Ocular cancer 
  • Ocular infection 
  • Delayed skin wound healing  
  • Glaucoma 
  • Neuroprotection 
  • Cataract formation 
  • Herpetic keratitis 
  • Ocular vascularization 
  • Corneal wound healing 
  • Corneal transplantation 

Rabbit models: 

  • Rabbit-induced dry eye 
  • Rabbit uveitis 
  • Corneal wound healing using an excimer laser 

Other animal models:

  • Dog: spontaneous dry eye, corneal wound healing, implantable corneal devices 
  • Feline models of herpetic keratitis 

If the model you seek is not listed, let OSOD know.  We may very well have the validated model in one of our laboratories, and if not, we can probably help you locate it through our network of collaborations and our knowledge within the field.